HDAC1 and Friedreich ataxia: This compound has a Ki value of 14 nM for HDAC3, which was 10 times lower than the Ki for HDAC1 [55,56], while its analog, RGFP109, which is also used as a promising treatment for Friedreich’s ataxia, shows a better potency for HDAC3 with the Ki value of 5 nM, and 32 nM for HDAC1 [57].