CFTR and cystic fibrosis: For instance, one strategy that was successful in the clearance of the Illumina MiSeqDX Cystic Fibrosis 139‐Variant Assay48 was to leverage information from the cystic fibrosis transmembrane conductance regulator CFTR2 database49 which is a high quality, well curated database that aggregates evidence from patients around the globe to establish the link between specific variants in the CFTR gene and the disease.