In our study, we disclosed that: (1) 10 probable EBV EA, MA, LMP-1, and LMP-2A B-cell epitopes related to SLE were predicted by analyzing amino acid sequences, secondary structures, transmembrane domains, surface properties, and homological comparison between the epitopes and SLE self-antigens. The gene discussed is PDLIM7; the disease is systemic lupus erythematosus.