As to determine the possible EBV EA, MA, LMP-1, and LMP-2A B-cell epitopes with high homology to SLE self-antigens, amino acid sequences of EA, MA, LMP-1, and LMP-2A were compared with SLE self-antigens, including SmB, SmD, SmE, rRNP, and Ro, and we observed 10 candidate B-cell epitopes named Epitope 1–10 as shown in Table 2. Here, SNRPE is linked to systemic lupus erythematosus.