In addition, serum samples from SLE patients and HCs were obtained, subsequently indirect ELISA was performed and we found serum EP1, EP2, EP3, EP4, EP6, and EP10 levels were increased in SLE patients compared with HCs, while after Bonferroni correction, only EP1, EP3, EP4, and EP6 levels were elevated. The gene discussed is PTGER4; the disease is systemic lupus erythematosus.