However, there are many similarities between cases of FTDP-17T and other pure Tauopathies, such as sporadic progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), argyrophilic grain disease (AGD), and Pick’s disease, especially with regard to the isoform composition of Tau filaments. Here, MAPT is linked to argyrophilic grain disease.