A wider search in the GWAS catalog revealed that SNPs in high LD (R2 > 0.6) with rs61765646 (NEGR1) were previously associated with obesity; rs17362588 (CCDC141/TTN but not the independent SNP rs35596070) and rs12906962 (MCTP2) with diastolic blood pressure and rs7072737 (PAX2) with systolic blood pressure; and rs4963772 (BCAT1) with PR interval and rs1997571 (CAV1) with atrial fibrillation and PR interval (Supplementary Data 7). The gene discussed is CCDC141; the disease is obesity due to melanocortin 4 receptor deficiency.