Litchi seed extracts were found to possess diverse pharmacological effects including significantly inhibiting cell viability and clonogenic growth of prostate cancer PC-3, DU145, RM-1, and C4-2B cells in a dose-dependent manner (31.25–250 μg/mL) and inducing cell apoptosis and cell cycle G1/S phase arrest by inactivating protein kinase B (Akt or PKB) signaling pathway [31]. The gene discussed is AKT1; the disease is Familial prostate cancer.