In addition, reduced expression of miR-29 family causes several neurodegenerative disorders, including Alzheimer’s disease, Huntington’s disease, and spinocerebellar ataxias, by targeting voltage-dependent anion channel 1 (VDAC1), β-secretase 1 (BACE1) and neuron navigator 3 (NAV3) [54,55,56,57]. The gene discussed is BACE1; the disease is early-onset autosomal dominant Alzheimer disease.