Exploring that possible mode of action, Ju and colleagues demonstrated that octreotide-modified liposomes containing daunorubicin and dihydroartemisinin blocked tumor cell migration in vitro, through the regulation of E-cadherin, α5β1-integrin, transforming growth factor beta 1 (TGF-β1), vascular endothelial growth factor (VEGF), and matrix metalloproteinase-2/9 (MMP2/9) in breast cancer cells [16]. This evidence concerns the gene TGFB1 and breast carcinoma.