Figure 2 shows the dilated cardiomyopathy pathway from the KEGG pathway database [34] overlaid with genes reported in the literature to have deleterious mutations associated with IDC (depicted in red font) and genes associated with IDC based on GWA analysis of our dataset (depicted in blue font). Note that MYH7 and SGCD, which are modestly, albeit not significantly, associated with IDC in our current GWAS, have mutations reported in IDC cases. The central role of voltage-gated L-type calcium channels in regulating intracellular Ca2+ is shown. The gene discussed is MYH7; the disease is dilated cardiomyopathy.