We divided MI-induced heart failure into three groups: MI-induced heart failure treated with intracerebroventricular (ICV) infusion of AT1R blocker (ARB, losartan) (HF-ARB, n = 5), or with ICV infusion of Nrf2 activator, tert-butylhydroquinone (tBHQ) (HF-tBHQ, n = 5), or simply with ICV infusion of vehicle (HF-VEH, n = 5). This evidence concerns the gene AGTR1 and heart failure.