CD40LG and Epstein-Barr virus infection: However, unlike past EBV infection, prevalence of EBV VCA-IgM, a parameter of acute EBV infection, was 12.2% (120/983) in 0–10 year old children patients in our study, which was much higher than the 1.6%-2.7%/ positive rate in 1–10 year healthy children without the EBV-related symptoms [14].