In the meta-analysis of 25 case control studies of EBV and SLE, Hanlon P et al [26] reported that the seroprevalence of EBV VCA-IgG, IgA, and EA/D IgG antibodies, though possibly not anti-EBNA-1, were significantly higher in cases than controls. This evidence concerns the gene CD79A and systemic lupus erythematosus.