In earlier studies by Yousefi and co-workers, silencing of ATG5 in cultured human HeLa cervical or MDA-MA-231 triple negative breast cancer cells, with short interfering RNA (siRNA), rendered these cells more resistant to staurosporine or doxorubicin for several days and delayed cell death [31]. The gene discussed is ATG5; the disease is triple-negative breast carcinoma.