In vivo, the intravenous injection of DAB-Lf dendriplex encoding TNFα led to a tumor suppression for 70% of PC-3 and 50% of DU145 tumors, while treatment with DAB-Lf dendriplex encoding TRAIL led to tumor suppression of 40% of PC-3 tumors and 20% of DU145 tumors. This evidence concerns the gene TNF and neoplasm.