SIRT1 and Alzheimer disease: Being SIRT1 directly involved in the regulation of the oxidative stress, whose levels were demonstrated to be extremely high in the brain of AD subjects [68, 69], we measured the functionality of redox enzymes and the amount of well-established markers of proteins, lipid and DNA oxidation to evaluate if the SLAB51-induced activation of SIRT1 pathway effectively corresponded to an antioxidant action.