NES and muscular dystrophy: Interestingly, in a pig model of muscular dystrophy, nestin protein levels were robustly increased (33-fold) in skeletal muscle and the intermediate filament protein was re-expressed in regenerating skeletal tissue of mice muscle following denervation (Carlsson et al., 1999; Vaittinen et al., 1999; Fröhlich et al., 2016).