CD4 and infection: With ART initiation thresholds based on time elapsed since infection (withoutconsideration of CD4 count or stage of infection), virulence was slightlyincreased by 2020 (8 years after ART rollout), except in scenarios with 100%coverage, in which mean SPVL was increased by 0.2 log10 withinitiation at 3 years after infection (Fig. 2).