Samples of group B compared with those of group C are prevalently localized on the left colon (p = 0.02), are associated with adenocarcinoma histological type (p < 0.0001), G1/G2 tumor grade (p < 0.0001), massive TANs (p = 0.0005), N0 status (p = 0.05), BRAF wild-type (p = 0.007) and microsatellite stability status (MSS) (p = 0.008). This evidence concerns the gene BRAF and adenocarcinoma.