Among the 12 previously reported series involving in all 1072 adult soft tissue sarcomas studied for EGFR expression, EGFR was frequently expressed in malignant fibrous histiocytomas, myxofibrosarcomas, synovial sarcomas and malignant peripheral sheath tumors, but few DFSP samples were tested [13–24]: 5 samples were negative in immunohistochemistry (IHC), and 4 others showed EGFR mRNA expression on Northern blot [14,22–24]. Here, EGFR is linked to histiocytoma.