The same pattern of expression, both on areas of local extension and on areas of higher-grade sarcoma, was found for EGFR mRNA in laser-microdissected cells (Figure 2): a significant increase was found in the DFSP infiltrative periphery compared to the DFSP center (1.11 ± 0.21 vs 0.32 ± 0.08; p < 0.01); the mean level of EGFR mRNA was highly elevated in DFSP-T, but no significant difference was observed between the DFSP-T and DFSP infiltrative periphery due to variation in EGFR mRNA expression among DFSP-T samples (DFSP-T, 3.98 ± 3.7 vs DFSP periphery, 1.11 ± 0.21; p > 0.20). Here, EGFR is linked to sarcoma.