Expression level of PRDX1 was validated to be the predictors for DFS (P = 0.002 in Univariate-analysis and P = 0.001 in multivariate-analysis; Table IV) and OS (P = 0.005 in Univariate-analysis and P = 0.004 in multivariate-analysis; Table 3) in osteosarcoma. This evidence concerns the gene PRDX1 and osteosarcoma.