TNF and endothelial dysfunction: Moreover predictive value of NLR is comparable to various other inflammatory markers such as C – reactive protein (CRP), tumor necrosis factor (TNF-α) and interleukin (IL-6) in the detection of subclinical inflammation and endothelial dysfunction in various clinical studies.5,6 NLR, a traditional marker has various advantages over other inflammatory markers because of its wide availability, low cost, reliability, easy lab detection.