GC and vitamin D deficiency: Previous studies revealed no effect of VDBP genotype distribution on the risk of CHD.11,12 These findings can be explained by the fact that these studies were conducted on non-Asian populations and thus may not apply to Asian populations due to ethnic variations in the frequency distribution of VDBP genotypes.20 Our study is the first large study to report the association of vitamin D deficiency and AMI in a Pakistani population.