TIMP3 and cancer: miR-21 promotes migration of cancer cells by targeting Reversion Inducing Cysteine-Rich Protein with Kazal motifs (RECK), TIMP metallopeptidase inhibitor 3 (TIMP3), and T-Cell Lymphoma Invasion And Metastasis 1 (TIAM1) genes (Gabriely et al., 2008; Cottonham et al., 2010).