Niflumic acid is also a TRPV1 channel antagonist and it was reported that peripheral neuropathy by suppressing excessive ROS, RNS, inflammatory cytokine production and TRPV1 activation in neuropathic pain-induced rats were recovered by the niflumic acid treatment (Marwaha et al., 2016). The gene discussed is TRPV1; the disease is peripheral neuropathy.