FGFR2 and endometrial cancer: To investigate mechanisms of acquired resistance to FGFR inhibitors, we adopted endometrial cancer cell line models, with two cell lines that harbor FGFR2 activating mutations, MFE-296 and AN3CA cells (Byron et al., 2008), and one that expresses wild-type FGFR2, Ishikawa cells (Byron et al., 2013).