Within yellow module,ADORA3 (30), TLR7 (31), IR4 (32), and CCR4(33, –35) are genesclosely related to lymph node metastasis and survival of GC, and within turquoisemodule, two miRNAs (miRNA-183 and miRNA-942) (13,36) and three genes (GNAO1, ISM1andSLIT2) are factors involved in the regulation of GC. The gene discussed is CCR4; the disease is gastric cancer.