KEGG pathway analysis showed that a total of 99 candidate target genes (DU vs CE, 44 genes; DU vs CO, 33 genes; CE vs CO, 29 genes) were significantly annotated to 4 pathways (DU vs CE, “MAPK signaling pathway”; DU vs CO, “Bacterial invasion of epithelial cells” and “Pancreatic cancer”; CE vs CO, “PI3K-Akt signaling pathway”). The gene discussed is AKT1; the disease is familial pancreatic carcinoma.