UGT1A1 and Decreased total neutrophil count: As shown in Supplementary Table 5, a significant association was found between UGT1A1 variants and neutropenia (P = 0.001) with higher risk for UGT1A1*28/*28 (OR, 3.75 [95% CI, 1.80–7.80]) than UGT1A1*1/*28 variants (OR, 1.66 [95% CI, 1.07–2.59]), both compared with the UGT1A1*1/*1 group.