Merosin-deficient CMD type 1A (MDC1A), caused by mutations in the LAMA2 gene, constitutes approximately 50% of total CMD cases and is characterized by hypotonia within the first several months of life, increased levels of serum creatine kinase (CK), multiple joint contractures, and white matter abnormalities (Herrmann et al., 1996; Cohn et al., 1998; Pegoraro et al., 1998). Here, LAMA2 is linked to congenital muscular dystrophy.