CD4 and allergic rhinitis: Ping and colleagues showed, in allergic rhinitis (AR) patients, that the AhR modulated the increased secretion of IL-10 in DCs and CD4+ T cells, reduced expression of IL-1β and IL-6 in DCs and IL-17 in CD4+ T cells, via ITE treatment, and subsequently inhibited the response of T-helper (Th)17 cells to suppress the AR (113).