Furthermore, MRictor−/− → Ldlr−/− mice also had significantly decreased atherosclerosis in the aortic sinus (42%), a smaller CD68 + macrophage area and more TUNEL-positive cells in the atherosclerotic lesions than lesions of control male Rictorfl/fl → Ldlr−/− recipients (Figures 6D–F). This evidence concerns the gene CD68 and atherosclerosis.