To illustrate the effects of EGR1 or c-FOS on the regulation of BD2 and BD3-mediated clearance of PA, THP-1 macrophages were transfected with EGR1 or c-FOS plasmids, then treated with BD2 or BD3 peptides for 6 h, which was followed by PA infection (MOI = 25). Here, FOS is linked to infection.