ANXA5 and type 2 diabetes mellitus: Annexin V negative and total VCAM-1 positive MPs were significantly higher in participants with T2DM compared to controls (248 ± 130 vs. 144 ± 68, p = 0.04; 314 ± 130 vs. 196 ± 65, p = 0.02, respectively) indicating impaired baseline endothelial function in participants with T2DM compared to the controls.