Ectopic NRF1 and NRF2 abrogated g#5-induced downregulation of PSMβ5 mRNA (Fig. S6e-f) and rescued the effects on MM cell viability (Fig. 3b), suggesting a significant role of NRF1/2 on the oncogenic potential of MALAT1 in MM. The gene discussed is MALAT1; the disease is Miyoshi myopathy.