In agreement with previous studies6,7,10,14,16,18,22,23, we found that PNPLA3 rs738409, GCKR rs1260326, TM6SF2 rs58542926 and MBOAT7 rs641738, but not the other GWAS identified variants14, were genetic contributors to NAFLD in our cohort. The gene discussed is GCKR; the disease is metabolic dysfunction-associated steatotic liver disease.