Furthermore, the predictive value of intratumoral AGO1 expression within subgroups (AFP: ≤20 vs >20 ng/ml; tumor size: ≤5 cm vs >5 cm; HBsAg status: positive vs negative) was investigated, and the prognostic significance of AGO1 was retained: AFP subgroup (P = 0.001 and 0.008, respectively; Fig. 7c, d); tumor size subgroup (P = 0.002 and 0.007, respectively; Fig. 7e, f); and HBsAg status subgroup (P = 0.005 and 0.002, respectively; Fig. 7g, h). The gene discussed is AFP; the disease is neoplasm.