LAMA2 and Sepsis: In recent years, the activation of skeletal muscle autophagy has been demonstrated under various conditions and disease states ranging from fasting [15, 16], oxidative stress [17], denervation [18, 19], and drug effects [20, 21] to systemic diseases, such as sepsis [22], merosin-deficient congenital muscular dystrophy (MDC1A) [23], and cancer [16].