Figure 4 shows the predicted genes carrying functional mutations in three cancers. By checking the published literature, we found that most of the genes have been implicated for important roles in oncogenesis [6]. However, there are mutation preferences among three cancer types. As showed in Figure 4, only TP53 gene is shared by all three cancer types and NF1 gene is shared by OV and GBM. This evidence concerns the gene NF1 and cancer.