DMD and Duchenne muscular dystrophy: 2010). DMD is characterized by the absence of the cytoskeletal protein dystrophin, which anchors the contractile apparatus of the skeletal muscle to the extracellular matrix providing myofibers with stability during contraction. Without dystrophin, myofibers become highly susceptible to contraction‐induced damage and/or ion channel dysfunction leading to Ca2+ influx and the subsequent activation of proteases and myofiber necrosis (for recent review, see Allen et al. (2016)).