Interestingly, an IGVH-mutated-CLL patient also had a high level of SOX11 compared to the calibrator: 80 [1–80], 66 [0.2–66], and 72 [0.4–72] respectively for GAPDH, RPLP0 and both housekeeping genes. The gene discussed is RPLP0; the disease is B-cell chronic lymphocytic leukemia.