Vervets display AD‐like pathology, including accumulation of Aβ‐containing cerebral plaques associated with reactive astrocytosis, dystrophic neurites, and vascular Aβ immunoreactivity resembling cerebral amyloid angiopathy (CAA), but unlike humans have relatively preserved cognition that does not appear correlated with plaque burden and demonstrate scant phosphorylated tau aggregates (Heuer et al., 2012; Kalinin et al., 2013; Lemere et al., 2004; Toledano et al., 2014). Here, MAPT is linked to Alzheimer disease.