The result of binary logistic regression (groups [DNR vs. DR] as the dependent variable and age, age on set, duration of diabetes, BMI, hypertension [%], HbA1c, FPG, TG, TC, LDL-C, HDL-C, albuminuria, plasma urea, plasma creatinine, ACR, AER, and ACE, AGT genotype as covariates) indicated that no significant relationship was found about the ACE and AGT gene polymorphisms with diabetic retinopathy after adjusting for confounding factors (Table 3). The gene discussed is ACE; the disease is diabetes mellitus.