NOS2 and hepatocellular carcinoma: NOS2 and arginiase-1 levels increased in MCF-7, Hs578T, and HCC-38 exosome-treated RAW264.7 cells relative to PBS-treated cells, and CD206, FIZZ-1, and YM-1 mRNA expressions were undetectable or decreased in MCF-7, Hs578T, and HCC-38 exosome–treated RAW264.7 cells (Supplementary Figure 3).