For comparison, Figure 1D also shows the peak-calling results for several other genes: NFIB and NOTCH1, which have been implicated as important in ACC tumors and are expressed in most, but not all of the samples from all three groups, and VGLL3, an example of a gene that was expressed only in samples that expressed neither MYB nor MYBL1. The VGLL3 gene encodes a transcription factor implicated in other epithelial tumors [26, 27], but its importance in ACC has not been established. The gene discussed is NOTCH1; the disease is adrenal cortex carcinoma.