RIS-1/psoriasin is expressed in primary keratinocytes, SZ95 sebocytes and primary fibroblasts, but not in primary melanocytes, the immortalized vascular endothelial cell line HMEC-117 and the human promyelocytic leukemia cell line (HL-60) (Fig. 1). The gene discussed is S100A7; the disease is acute promyelocytic leukemia.