THSD7A-positive MN is associated with malignancy, as THSD7A itself may also play a role in certain cancers (331) and specifically two cases were described, one with gallbladder carcinoma, one with endometrial cancer, where THSD7A was overexpressed in the tumor and taken up by follicular dendritic cells in a regional lymph node (106, 113, 115, 116). This evidence concerns the gene THSD7A and gallbladder carcinoma.