Levels of prostaglandin E2 (PGE2), TXA2, and IL-6 were significant higher in aortic aneurysms and were associate with overexpression in the aneurysmal wall of the inflammatory cyclooxygenase 2 (COX2) (Cheuk and Cheng, 2007). This evidence concerns the gene PTGS2 and aortic aneurysm.