PRKN and Parkinson disease: Finally, the crucial link between inflammation and PD is further exemplified by the fact that key PD-associated genes, such as α-Syn (SNCA), PARK2, deglycase (DJ-1), leucine-rich repeat kinase 2 (LRRK2), and glucocerebrosidase (GBA) are all expressed in immune cells, suggesting their potential to modulate inflammation (Dzamko et al., 2015).