We found that on day 10 after EAE induction (day of onset), expression of EGFL7 was slightly decreased (intensity) or comparable (relative intensity) to expression in naïve control, however on day 14 (peak of disease) and most strikingly on day 25 (remission/chronic), similar to our observations in MS brain tissue, we observe that EGFL7 expression is increased in CNS vasculature of EAE mice (Fig. 3a–c). The gene discussed is EGFL7; the disease is myeloid sarcoma.