Tumor CXCL13 content also had an independent influence on DDFS in a multivariable analysis adjusted for age at the time of study entry, tumor size, axillary nodal status, and histological grade of differentiation (HR 0.39, 95% CI 0.19–0.79; P = 0.009; Table 3). Here, CXCL13 is linked to neoplasm.