ESR1 and breast neoplasm: Breast tumor expression of CXCL13 (Table 1) and of FOXP3 (Additional file 5: Table S3) above the median value were both associated with poor histological grade of differentiation, negative ER and PR status, positive HER2 status, Ki-67 expression above the median value, and with the HER2-positive and the TNBC molecular subtypes, whereas CD4 (Additional file 6: Table S4) expression was not associated with these variables.