OxA promoted proliferation and viability in human gastric cancer cells SGC-7901 with activation of the ERK1/2-MAPK pathway [74], human adrenocortical adenomas [75], in immortalised primary embryonic rat hypothalamic R7 cells [76], 3 T3-L1 preadipocytes [77] and in rat hepatocytes [78]. This evidence concerns the gene MAPK3 and adrenal cortex adenoma.